Identifying the exact cause is essential for proper treatment .Investigations are done to detect the cause of infertility.
Causes of infertility – male factors -30%, female factors 30%, combined 30%,unexplained – 10%
Causes of infertility – male factors -30%, female factors 30%, combined 30%,unexplained – 10%
Diagnosis is done after the couple is subjected to the following:
- History – personal and family
- Examination – of the male and female partner
- Tests and other procedures
Evaluation of Male partner:
Not all the tests are needed for all patients.
General health, HIV , HBS AG & HCV are to be tested .
Basic investigation of Male
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Investigation
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Purpose
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Semen analysis
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Know the total sperm count, motility, normality of sperms and other parameters.
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Hormonal analysis by blood test: FSH, LH, Testosterone and Prolactin.
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Know the cause of Azoospermia.
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Scrotal Ultrasound
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Distinguish varicocele from other testicular lesions
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Semen C&S
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To rule out infection.
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Chromosomal analysis
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In cases involving severely defective spermatogenesis genetic counseling and testing is offered.
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Counseling
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About investigation result and future treatment.
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Note: Semen taken after 2-7 days of sexual abstinence. Semen ejaculated by masturbation in special container at home, hotel or hospital. .
The above procedures are done with one sample of semen
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Evaluation of female partner:
Age of the female partner is an important factor in fertility and as a woman becomes older her fertility diminishes.
General health, HIV, HBS AG, HCV, HB estimation (should be >10 g before embarking upon IVF treatment.
Basic investigation of Female
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Investigation
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Purpose
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Hormonal evaluation
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Baseline levels of FSH, LH on day -2 or day 3- of the menstrual cycle is estimated which predicts the ovarian reserve .Other hormones like TSH and Prolactin are also estimated. Inhibin & Anti mullerian hormone gives additional information.
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Baseline Ultra Sound Scanning
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To assess the uterus and ovaries –to rule out fibroids, cysts, to assess the number of available follicles, and ovarian volume and accessibility of the ovaries during ovum pick up.
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Hysterosalpingogram
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Assess the uterine cavity and tubal patency
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Hysterolaparoscopy
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Indicated in some cases
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Trial ET
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Anticipate and rectify any difficulty during actual embryo transfer.
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Counseling
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To explain the procedure, complications, success rates and to clear any doubts of patients.
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One menstrual cycle (one month): From Day2 (D2) of the menses for one month is needed for observing/ checking the varying structural, functional and hormonal changes in uterus and ovary. For IVF treatment, next / another menstrual cycle is selected.
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